General Information

  • ID:  hor003592
  • Uniprot ID:  P84374
  • Protein name:  Periviscerokinin-2 type 1
  • Gene name:  NA
  • Organism:  Celatoblatta sp. (strain Blue Mountains) (Cockroach)
  • Family:  Periviscerokinin family
  • Source:  animal
  • Expression:  Abdominal perisympathetic organs.
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  unclassified Celatoblatta, Celatoblatta (genus), Blattinae (subfamily), Blattidae (family), Blattoidea (superfamily), Blattodea (order), Dictyoptera (superorder), Polyneoptera (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  GO:0005576 extracellular region

Sequence Information

  • Sequence:  GSASGLISMPRV
  • Length:  12
  • Propeptide:  GSASGLISMPRV
  • Signal peptide:  NA
  • Modification:  T12 Valine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Myotropic activity
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor003592_AF2.pdbhor003592_ESM.pdb

Physical Information

Mass: 137076 Formula: C49H87N15O16S
Absent amino acids: CDEFHKNQTWY Common amino acids: S
pI: 10.55 Basic residues: 1
Polar residues: 5 Hydrophobic residues: 4
Hydrophobicity: 57.5 Boman Index: -520
Half-Life: 30 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 97.5
Instability Index: 3950 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  15626499
  • Title:  A proteomic approach for studying insect phylogeny: CAPA peptides of ancient insect taxa (Dictyoptera, Blattoptera) as a test case.